See the next section to read more about the mechanism. It is also worth noting that diabetes mellitus type 2 always coexists with insulin resistance (as insulin resistance is a background for the disease), so there might not be a reason to run the test. Remember that both values refer to the fasting state where nothing has been eaten or drank (other than clear water) for at least 8 hours before the blood sample is drawn.įor the glucose concentration in mmol/L, or:įor glycemia in mg/dL. The choice depends on the units you prefer to use. You can do your own HOMA formula calculation using one of the following equations. Keep in mind that this 'gold standard' method is limited to only scientific purposes. In contrast, the 'gold standard' method for diagnosing insulin resistance (a hyperinsulinemic euglycemic metabolic clamp) involves multiple intravenous administrations of insulin and glucose, along with measuring blood parameters numerous times. People widely use it because of its simplicity and noninvasive nature. HOMA-IR - HOmeostatic Model Assessment for Insulin Resistance - is an index used to determine if insulin resistance is present in a patient.
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